Could a fiber supplement improve PCOS heart risks?

NCT ID NCT06852365

Recruiting now Disease control Sponsor: University of Pennsylvania Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a daily fiber supplement (resistant starch, like Benefiber) can improve heart health markers and gut bacteria in women with polycystic ovary syndrome (PCOS). One hundred women will take either the fiber or a placebo for 12 weeks, alongside standard birth control pills. Researchers will measure changes in cholesterol, blood sugar, blood pressure, and gut microbes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: resistant starch (wheat dextrin, also known as Benefiber)
What this could lead to: If it works, this could point toward a simple dietary supplement to improve heart health and gut balance in women with PCOS.
What could go wrong: This is an early phase 2 trial with only 100 participants, so results may not apply to everyone. The supplement may show no benefit over placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

abdominal obesity-metabolic syndrome metabolic syndrome X polycystic ovary syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

METABOLIC SYNDROME POLYCYSTIC OVARY SYNDROME

Contacts and locations

Locations

University of Pennsylvania
RECRUITING

Philadelphia, Pennsylvania, 19104, United States

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