Exercise may counter muscle loss in transgender women on hormone therapy

NCT ID NCT07400419

Recruiting now Disease control Sponsor: Massachusetts General Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a 12-week home resistance exercise program can help transgender women and gender-diverse individuals starting estrogen-based hormone therapy maintain muscle mass and strength. Hormone therapy can increase the risk of muscle loss (sarcopenia), which may lead to health problems. Participants will be randomly assigned to either an exercise group or a counseling-only group to see if exercise helps preserve muscle and improve well-being.

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Conditions

The condition(s) this trial relates to.

Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MUSCLE MASS AND STRENGTH

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02114, United States

Contact Email: •••••@•••••

Contact Phone: •••-•••-•••• Email: •••••@•••••