Exercise may counter muscle loss in transgender women on hormone therapy
NCT ID NCT07400419
First seen Jun 27, 2026 · Last updated Jul 14, 2026 · Updated 2 times
Summary
This study looks at whether a 12-week home resistance exercise program can help transgender women and gender-diverse individuals starting estrogen-based hormone therapy maintain muscle mass and strength. Hormone therapy can increase the risk of muscle loss (sarcopenia), which may lead to health problems. Participants will be randomly assigned to either an exercise group or a counseling-only group to see if exercise helps preserve muscle and improve well-being.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
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