Exercise plus Rg1 supplement may awaken stem cells to fight muscle loss in aging women

NCT ID NCT07703774

Not yet recruiting Knowledge-focused Sponsor: University of Taipei Source: ClinicalTrials.gov ↗

First seen Jul 14, 2026 · Last updated Jul 23, 2026 · Updated 3 times

Summary

This study investigates whether a supplement called Senactiv® (containing Rg1) combined with resistance exercise can help women over 60 build muscle by recruiting bone marrow-derived stem cells. Participants will do leg squats four times a week, with or without the supplement. Researchers will measure stem cell activity in muscle tissue to see if the combination works better than exercise alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: an Rg1-based supplement called Senactiv®
What this could lead to: If it works, this could point toward a supplement-and-exercise strategy to prevent age-related muscle loss (sarcopenia) in older women.
What could go wrong: This is a small, early-stage study with 60 participants, so results may not apply broadly. The supplement's effect on stem cells is still uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BONE MARROW-DERIVED CELLS MUSCLE MASS AND STRENGTH MYELOID CELL INFILTRATION

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