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Exercise plus Rg1 supplement may awaken stem cells to fight muscle loss in aging women

NCT ID NCT07703774

Knowledge-focused Sponsor: University of Taipei Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 14, 2026 · Last updated Jul 23, 2026 · Updated 3 times

Summary

This study investigates whether a supplement called Senactiv® (containing Rg1) combined with resistance exercise can help women over 60 build muscle by recruiting bone marrow-derived stem cells. Participants will do leg squats four times a week, with or without the supplement. Researchers will measure stem cell activity in muscle tissue to see if the combination works better than exercise alone.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
an Rg1-based supplement called Senactiv®
What this could lead to
If it works, this could point toward a supplement-and-exercise strategy to prevent age-related muscle loss (sarcopenia) in older women.
What could go wrong
This is a small, early-stage study with 60 participants, so results may not apply broadly. The supplement's effect on stem cells is still uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Jan 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 90 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: \- Must be able to swallow pills

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bone marrow-derived cells Muscle mass and strength Myeloid cell infiltration

How to take part

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  1. The official record

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    Open the record ↗

  2. A doctor treating you

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