Could zapping kidney nerves ease heart failure?

NCT ID NCT07558902

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a procedure called renal denervation (RDN) in 20 people with heart failure. Doctors use a thin tube to deliver radiofrequency energy to nerves around the kidney arteries, aiming to reduce stress on the heart. Participants continue their usual heart failure medications and are monitored for 6 months to see if the procedure lowers a key heart strain marker (NT-proBNP) and improves walking distance.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

renal denervation procedure using a multi-channel radiofrequency ablation system

What this could lead to

If successful, this could point toward a new procedure to help control heart failure symptoms and reduce strain on the heart.

What could go wrong

This is a very early, small study with only 20 participants and no comparison group. The procedure involves risks like bleeding or vessel damage, and benefits may not be confirmed in larger trials.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Zhongshan Hospital Fudan University

    Shanghai, Shanghai Municipality, 200030, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••