Could zapping kidney nerves ease heart failure?

NCT ID NCT07558902

Not yet recruiting Disease control Sponsor: Shanghai Golden Leaf MedTec Co. Ltd Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a procedure called renal denervation (RDN) in 20 people with heart failure. Doctors use a thin tube to deliver radiofrequency energy to nerves around the kidney arteries, aiming to reduce stress on the heart. Participants continue their usual heart failure medications and are monitored for 6 months to see if the procedure lowers a key heart strain marker (NT-proBNP) and improves walking distance.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: renal denervation procedure using a multi-channel radiofrequency ablation system
What this could lead to: If successful, this could point toward a new procedure to help control heart failure symptoms and reduce strain on the heart.
What could go wrong: This is a very early, small study with only 20 participants and no comparison group. The procedure involves risks like bleeding or vessel damage, and benefits may not be confirmed in larger trials.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HEART FAILURE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART FAILURE

Contacts and locations

Locations

Zhongshan Hospital Fudan University

Shanghai, Shanghai Municipality, 200030, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.