Brain tumor evolution tracked by advanced imaging in small trial

NCT ID NCT05386043

First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 34 times

Summary

This study looks at how brain tumors (gliomas) change over time and whether advanced MRI and PET scans can predict those genetic changes. Twenty adults with suspected or confirmed glioma will have special PET scans before surgery, and their tumor tissue will be analyzed. The goal is to see if imaging can replace repeated biopsies and help guide treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Indiana University School of Medicine

    RECRUITING

    Indianapolis, Indiana, 46202, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

FET F-18, O-15 Radioisotope

What this could lead to

If successful, this could lead to better imaging methods that predict tumor mutations without repeated biopsies.

What could go wrong

This is a small, early-stage study with only 20 participants, so results may not apply to all glioma patients. The imaging tools are experimental and may not reliably predict mutations.

Conditions

The condition(s) this trial relates to.

glioblastoma glioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.