Could a tooth-based gel save kids' teeth? new trial explores regenerative dental treatment

NCT ID NCT07210359

Recruiting now Disease control Sponsor: Kafrelsheikh University Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether two forms of demineralized dentin matrix (a material made from tooth tissue) can help regenerate immature permanent teeth in children aged 9 to 15. The trial compares these materials to a standard sealing material called RetroMTA. Over 12 months, researchers will check if the treatments improve root growth and healing. The goal is to find a better way to treat damaged teeth and avoid tooth loss.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: demineralized dentin matrix (DDM) and RetroMTA
What this could lead to: If successful, this could offer a better way to help damaged immature teeth grow stronger roots and heal, potentially saving teeth that might otherwise be lost.
What could go wrong: This is a small, early-stage trial with only 36 participants, so results may not apply to everyone. The materials are still experimental, and long-term success is uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

dental pulp necrosis pulpitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PULPAL NECROSIS

Contacts and locations

Locations

KafrelsheikhU
RECRUITING

Kafr ash Shaykh, Kafr Elsheikh, 33511, Egypt

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