New combo therapy aims to shrink rectal tumors before surgery

NCT ID NCT07284992

First seen Jan 06, 2026 · Last updated May 16, 2026 · Updated 20 times

Summary

This study tests two different radiation schedules (short-course vs long-course) combined with an immunotherapy drug (Adebrelimab) and chemotherapy before surgery for people with locally advanced rectal cancer. The goal is to see which approach better shrinks or eliminates the tumor before surgery. About 208 adults with operable rectal cancer will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Shandong Provincial Hospital Affiliated to Shandong First Medical University

    RECRUITING

    Jinan, Shandong, 250021, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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