New combo therapy aims to shrink rectal tumors and save the rectum

NCT ID NCT07469306

First seen Apr 10, 2026 · Last updated May 16, 2026 · Updated 7 times

Summary

This study tests two different radiation schedules combined with chemotherapy and an immunotherapy drug (tislelizumab) in 130 people with locally advanced rectal cancer. The goal is to see which approach leads to a complete disappearance of the tumor, potentially allowing patients to avoid surgery and keep their rectum. Participants must have a specific type of rectal cancer (MSS/pMMR) and be in good overall health.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fujian Cancer Hospital

    Fuzhou, Fujian, 350014, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Jinjiang Municipal Hospital

    Quanzhou, Fujian, 362200, China

    Contact Phone: •••-•••-••••

  • The Second Hospital of Longyan

    Longyan, Fujian, 364000, China

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.