New hope for HER2+ breast cancer patients who stopped responding to standard therapy

NCT ID NCT07366840

First seen Jan 27, 2026 · Last updated Jun 02, 2026 · Updated 13 times

Summary

This study tests a new drug combination (RC48 plus chemotherapy) against standard treatment (trastuzumab/inetetamab plus chemotherapy) in people with HER2-positive advanced breast cancer whose disease worsened after prior therapy with a topoisomerase I inhibitor antibody-drug conjugate. About 268 participants will be enrolled to see if the new combo improves progression-free survival. The goal is to find a better treatment option for this specific group of patients.

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Contacts and locations

Study contacts

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Conditions

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