Real-World study tracks Ravulizumab's impact on rare kidney disease

NCT ID NCT07399730

First seen Jun 24, 2026 · Last updated Jul 08, 2026 · Updated 3 times

Summary

This study will follow about 80 Polish patients with atypical hemolytic uremic syndrome (aHUS) who are receiving ravulizumab (Ultomiris) as part of routine care. Researchers will collect data from medical records and follow patients over time to see how well the drug controls the disease, including its effects on blood clotting and kidney function. The goal is to understand real-world outcomes of ravulizumab treatment in this rare condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
ravulizumab (Ultomiris)
What this could lead to
If successful, this study could confirm that ravulizumab effectively controls aHUS in real-world settings, helping maintain kidney function and reduce blood clotting complications.
What could go wrong
This is an observational study, not a controlled trial, so results may be less definitive. It only includes Polish patients, so findings may not apply to other populations.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Research Site

    NOT_YET_RECRUITING

    Gdansk, Poland

  • Research Site

    NOT_YET_RECRUITING

    Katowice, Poland

  • Research Site

    RECRUITING

    Katowice, Poland

  • Research Site

    NOT_YET_RECRUITING

    Krakow, Poland

  • Research Site

    NOT_YET_RECRUITING

    Lodz, Poland

  • Research Site

    NOT_YET_RECRUITING

    Poznan, Poland

  • Research Site

    RECRUITING

    Poznan, Poland

  • Research Site

    NOT_YET_RECRUITING

    Warsaw, Poland

  • Research Site

    RECRUITING

    Warsaw, Poland

  • Research Site

    NOT_YET_RECRUITING

    Wroclaw, Poland

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