Does timing of blood pressure med matter for kidney protection? new trial investigates
NCT ID NCT07259512
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 4 trial tests whether taking ramipril once daily or split into two smaller doses works better for protecting kidney function in 80 adults with chronic kidney disease and heart failure. Over 30 days, researchers will measure changes in blood markers of kidney function, inflammation, and oxidative stress. The goal is to find the best dosing schedule to slow kidney decline in this high-risk group.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Ramipril (an ACE inhibitor)
- What this could lead to
- If successful, this study could show that splitting the ramipril dose improves kidney protection in patients with both chronic kidney disease and heart failure.
- What could go wrong
- This is a small, short-term trial (80 patients, 30 days) looking at biomarkers, not long-term outcomes. Results may not translate to better kidney or heart health over time.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
UNS Hospital
RECRUITINGKartasura, Central Java, Indonesia
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