New ECT technique aims to treat severe depression with fewer memory problems

NCT ID NCT05402657

Completed Symptom relief Sponsor: The George Institute Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new way of giving electroconvulsive therapy (ECT) for severe depression. The goal was to see if a different electrode placement on the head could reduce memory loss while still effectively treating depression. 156 adults with severe depression took part, receiving either the standard or the new ECT placement over about 4 weeks, followed by 24 weeks of follow-up. The study compared how well each type worked and how it affected memory.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MAJOR DEPRESSIVE EPISODE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Depression Depressive Disorder, Treatment-Resistant major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MAJOR DEPRESSIVE EPISODE

Contacts and locations

Locations

Emory University

Atlanta, Georgia, 30322, United States
Gold Coast University Hospital (GCUH)

Gold Coast, Queensland, 4215, Australia
Medical College of Georgia, Augusta University

Augusta, Georgia, 30912, United States
Medical University of South Carolina

Charleston, South Carolina, 29425, United States
Ramsay Clinic Albert Road

Melbourne, Victoria, 3004, Australia
Ramsay Clinic Lakeside

Warners Bay, New South Wales, 2282, Australia
Ramsay Clinic Northside

Sydney, New South Wales, 2065, Australia

More trials for these conditions

Other studies related to the condition(s) this trial covers.