Decoding depression: sleep rhythms as biomarkers?

NCT ID NCT05866991

First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time

Summary

This study builds a large French cohort of 1,000 people experiencing a major depressive episode to examine their sleep and circadian rhythms. Researchers will use sleep recordings (polysomnography) and psychiatric evaluations to identify distinct patient subgroups and potential biomarkers. The goal is to better understand the biology of depression and pave the way for more personalized care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
This could help identify biological markers of depression, leading to more personalized diagnosis and treatment approaches.
What could go wrong
As an observational study, it cannot prove cause and effect. The findings may not translate into immediate clinical tools or benefit all patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hôpital Bichat Claude Bernard

    RECRUITING

    Paris, Paris, 75018, France

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