Can light be the new shield against radiation mouth sores?

NCT ID NCT06458517

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tests two light therapy devices—one placed inside the mouth and one outside—to prevent and treat painful mouth sores caused by radiation therapy. Sixty adults with oral cavity or oropharynx cancer will receive light sessions twice a week for prevention, then three times a week if sores appear. The goal is to see which device works better at reducing severe sores and treatment delays.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

light therapy (photobiomodulation) via CareMin650TM intraoral device and ATP38® transcutaneous device

What this could lead to

If successful, this could point toward a standard way to reduce painful mouth sores during radiation therapy for head and neck cancer.

What could go wrong

This is a small pilot study with only 60 people, so results may not apply to everyone. It is also not yet recruiting, so outcomes are uncertain.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

head and neck neoplasm Head and Neck Neoplasms oral cavity cancer oropharyngeal carcinoma oropharynx cancer stomatitis prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Institut de cancérologie Strasbourg Europe

    Strasbourg, 67033, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••