Centre Paul Strauss

This study tests whether giving a higher radiation dose to the most aggressive parts of a glioblastoma tumor, as seen on a special FDOPA PET scan, can help people live longer. It includes 75 adults who are too frail for standard treatment or had only a partial surgery or biopsy. …

This study tests whether using a special PET scan (FDOPA-PET) to guide radiation therapy can help people with recurrent glioblastoma, an aggressive brain cancer. About 54 participants will receive radiation precisely targeted to active tumor areas seen on the scan. The goal is to…

This study tests a combination of three drugs (carboplatin, paclitaxel, and cetuximab) in people with advanced head and neck cancer that has returned or spread. Participants must have already tried the immunotherapy drug pembrolizumab (with or without chemotherapy) and it stopped…

This study looks at whether a weekly cycling exercise program can help breast cancer patients maintain their physical fitness during chemotherapy. About 156 women with early-stage breast cancer will either do the cycling program or receive standard care. The goal is to see if the…

This study tests whether a special program of nutritional checks, medication review, and physical therapy can help people aged 75 and older complete their full course of chemotherapy for digestive cancer. About 144 participants will be randomly assigned to receive either the extr…

This study tests whether spending time with horses can improve quality of life and reduce anxiety in children and teenagers (ages 8-17) who are receiving radiotherapy for cancer. Participants will take part in 10 horse-assisted therapy sessions. The goal is to see if this approac…

This study is testing whether special PET-MRI scans can predict how well rectal cancer responds to chemotherapy and radiation before surgery. Researchers will scan 50 patients multiple times during treatment to see if early changes in the tumor can forecast the final outcome. The…

This study is collecting blood and tumor samples from 60 people with recurrent or metastatic head and neck cancer who are receiving standard anti-PD1 immunotherapy. The goal is to find biological markers that can predict whether the immunotherapy will work. Researchers will analy…

This study follows 80 cervical cancer patients who receive brachytherapy (internal radiation) to see if they develop post-traumatic stress disorder (PTSD). Participants fill out questionnaires about PTSD, anxiety, depression, quality of life, and sexual health over 5 years. The g…

This study aims to find genetic markers that may explain why some HER2-positive breast cancer patients respond well to treatment while others do not, or experience side effects. Researchers will collect blood samples from 9,000 participants and follow them for five years. The goa…

This study is collecting health data and biological samples from 15,000 people in Europe and Latin America to find markers that could predict gallbladder cancer risk or catch it early. Participants include patients with gallbladder cancer or gallstones. The goal is to improve pre…

This study aims to see if a newer type of scan, called PET/MRI, is better than the standard PET/CT scan at finding cancer spread in lymph nodes for people with cervical cancer. About 50 adults with stage IB2 to IVA cervical cancer will be enrolled. Researchers will compare the ac…

This study looks at whether a protein called SGLT2 is linked to heart damage caused by a common type of breast cancer chemotherapy. Researchers will measure SGLT2 levels in blood and cells from 50 women with localized breast cancer before and after treatment. The goal is to find …

This study is testing a special MRI technique called CEST to create detailed maps of acidity (pH) inside brain tumors like gliomas and metastases. Researchers will scan 800 patients who are already getting a PET/MRI for their brain tumor. The goal is to see if pH levels can help …

This study looks at how chemotherapy changes certain nerve reflexes that control blood pressure and exercise responses in breast cancer patients. Researchers will compare 24 women who recently finished chemotherapy with healthy volunteers. The goal is to understand these changes …