New hope for head and neck cancer: Triple-Drug combo tested after immunotherapy fails

NCT ID NCT06725368

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a combination of three drugs (carboplatin, paclitaxel, and cetuximab) in people with advanced head and neck cancer that has returned or spread. Participants must have already tried the immunotherapy drug pembrolizumab (with or without chemotherapy) and it stopped working. The goal is to see if this new combo can shrink tumors and control the disease for as long as possible. The study will enroll 46 adults in France and track their response for 12 months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

head and neck cancer Head and Neck Neoplasms head and neck squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU de Besançon

    RECRUITING

    Besançon, France

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre Hospitalier de Colmar

    RECRUITING

    Colmar, 68024, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Centre Paul Strauss

    RECRUITING

    Strasbourg, 67033, France

    Contact Email: •••••@•••••

    Contact

    Contact

    Contact

  • Centre hospitalier Régional de Metz-Thionville

    RECRUITING

    Ars-Laquenexy, 57085, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Institut de cancérologie de Lorraine

    RECRUITING

    Vandœuvre-lès-Nancy, 54519, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact