PET scan could sharpen radiation for returning brain tumors

NCT ID NCT05653635

Recruiting now Disease control Sponsor: Centre Paul Strauss Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether using a special PET scan (FDOPA-PET) to guide radiation therapy can help people with recurrent glioblastoma, an aggressive brain cancer. About 54 participants will receive radiation precisely targeted to active tumor areas seen on the scan. The goal is to see if this approach delays tumor regrowth compared to standard radiation planning.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: radiation therapy guided by FDOPA-PET imaging
What this could lead to: If successful, this could lead to a more precise radiation technique that delays tumor regrowth in recurrent glioblastoma.
What could go wrong: This is a small, early-phase trial (54 participants) and may not show a clear benefit. The approach is complex and may not work for all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

glioblastoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GLIOBLASTOMA

Contacts and locations

Locations

CHRU de Nancy
NOT_YET_RECRUITING

Nancy, De, 5400, France
Centre Paul Strauss
RECRUITING

Strasbourg, 67033, France

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