PET scan could sharpen radiation for returning brain tumors

NCT ID NCT05653635

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether using a special PET scan (FDOPA-PET) to guide radiation therapy can help people with recurrent glioblastoma, an aggressive brain cancer. About 54 participants will receive radiation precisely targeted to active tumor areas seen on the scan. The goal is to see if this approach delays tumor regrowth compared to standard radiation planning.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

radiation therapy guided by FDOPA-PET imaging

What this could lead to

If successful, this could lead to a more precise radiation technique that delays tumor regrowth in recurrent glioblastoma.

What could go wrong

This is a small, early-phase trial (54 participants) and may not show a clear benefit. The approach is complex and may not work for all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

glioblastoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHRU de Nancy

    NOT_YET_RECRUITING

    Nancy, De, 5400, France

    Contact Email: •••••@•••••

    Contact

  • Centre Paul Strauss

    RECRUITING

    Strasbourg, 67033, France

    Contact

    Contact Email: •••••@•••••

    Contact