New study aims to measure what matters most for kids with tough brain cancers

NCT ID NCT04670016

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study looked at how re-irradiation affects the quality of life and symptoms of 20 children with diffuse intrinsic pontine glioma (DIPG) or recurrent brain tumors, as well as their caregivers. Researchers used surveys to track physical, emotional, and social well-being over time. The goal was to better understand the real-world benefits and burdens of this treatment, not to test a new drug or cure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help doctors better understand how re-irradiation affects children's quality of life and guide supportive care for families.

What could go wrong

This is a small, non-therapeutic study with only 20 participants, so results may not apply broadly. It does not test a new treatment or cure.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

brain cancer diffuse intrinsic pontine glioma radiation injury Recurrence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Alberta Children's Hospital

    Calgary, Alberta, T3B 6A8, Canada

  • British Columbia Children's Hospital

    Vancouver, British Columbia, V6H 3N1, Canada

  • CHU de Quebec-Universite Laval

    Québec, G1V 4G2, Canada

  • CancerCare Manitoba

    Winnipeg, Manitoba, R3E 0V9, Canada

  • Centre hospitalier de l'Université de Montréal

    Montreal, Quebec, H3T 1C5, Canada

  • Children's Hospital

    London, Ontario, N6A 5W9, Canada

  • Children's Hospital of Eastern Ontario

    Ottawa, Ontario, K1H 8L1, Canada

  • IWK Health Centre

    Halifax, Nova Scotia, B3K 6R8, Canada

  • London Health Sciences Centre

    London, Ontario, N6A 5W9, Canada

  • McMaster Children's Hospital

    Hamilton, Ontario, L8N 3Z5, Canada

  • Princess Margaret Cancer Centre

    Toronto, Ontario, M5G 2M9, Canada

  • Stollery Children's Hospital

    Edmonton, Alberta, T6G 2B7, Canada

  • The Hospital for Sick Children

    Toronto, Ontario, M5G 1X8, Canada