New study aims to measure what matters most for kids with tough brain cancers

NCT ID NCT04670016

Completed Knowledge-focused Sponsor: University of Calgary Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study looked at how re-irradiation affects the quality of life and symptoms of 20 children with diffuse intrinsic pontine glioma (DIPG) or recurrent brain tumors, as well as their caregivers. Researchers used surveys to track physical, emotional, and social well-being over time. The goal was to better understand the real-world benefits and burdens of this treatment, not to test a new drug or cure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors better understand how re-irradiation affects children's quality of life and guide supportive care for families.
What could go wrong: This is a small, non-therapeutic study with only 20 participants, so results may not apply broadly. It does not test a new treatment or cure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

brain cancer diffuse intrinsic pontine glioma radiation injury Recurrence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRAIN TUMOR, DIPG BRAIN TUMOR, PEDIATRIC BRAIN TUMOR, PEDIATRIC, RECURRENT DIPG RADIATION EXPOSURE RADIATION TOXICITY

Contacts and locations

Locations

Alberta Children's Hospital

Calgary, Alberta, T3B 6A8, Canada
British Columbia Children's Hospital

Vancouver, British Columbia, V6H 3N1, Canada
CHU de Quebec-Universite Laval

Québec, G1V 4G2, Canada
CancerCare Manitoba

Winnipeg, Manitoba, R3E 0V9, Canada
Centre hospitalier de l'Université de Montréal

Montreal, Quebec, H3T 1C5, Canada
Children's Hospital

London, Ontario, N6A 5W9, Canada
Children's Hospital of Eastern Ontario

Ottawa, Ontario, K1H 8L1, Canada
IWK Health Centre

Halifax, Nova Scotia, B3K 6R8, Canada
London Health Sciences Centre

London, Ontario, N6A 5W9, Canada
McMaster Children's Hospital

Hamilton, Ontario, L8N 3Z5, Canada
Princess Margaret Cancer Centre

Toronto, Ontario, M5G 2M9, Canada
Stollery Children's Hospital

Edmonton, Alberta, T6G 2B7, Canada
The Hospital for Sick Children

Toronto, Ontario, M5G 1X8, Canada

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