Fiber fix? psyllium may tame fructan triggers in kids with IBS

NCT ID NCT06639984

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether psyllium, a common fiber supplement, can reduce belly pain and bloating in children with irritable bowel syndrome (IBS) who are sensitive to fructans—a type of sugar found in foods like wheat and onions. Researchers will give 110 kids aged 12-17 either psyllium or a placebo alongside fructan-containing meals, then track symptoms and gut bacteria changes. The goal is to see if psyllium can make fructans easier to digest.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
psyllium fiber
What this could lead to
If it works, this could point toward a simple fiber supplement to help children with IBS eat fructans without pain or bloating.
What could go wrong
This is an early phase 2 trial with only 110 participants, so results may not apply to all children. The benefit may be small or not work for everyone.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Duke University

    RECRUITING

    Durham, North Carolina, 27705, United States

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