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Mind over knee: new study reveals psychological key to ACL recovery

NCT ID NCT07201597

Knowledge-focused Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study examines the link between psychological readiness, knee function, and muscle strength in athletes who had ACL reconstruction surgery. Researchers will measure mental readiness using a special scale and test knee strength with a machine. The goal is to understand why some athletes successfully return to sport while others do not, combining both mental and physical factors.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help improve rehabilitation programs by showing that mental readiness is as important as physical strength for athletes returning to sport after ACL surgery.
What could go wrong
This is a small observational study with only 52 participants, so results may not apply to all athletes. It does not test a new treatment, so it won't directly change care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 52 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2025

An estimate. Start dates often move.

Expected to finish

Nov 2025

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consists of male recreational athletes who have undergone anterior cruciate ligament reconstruction using the Peroneus Longus tendon. These athletes must meet specific criteria to return to sport and will be evaluated for both physical and psychological readiness. Participants will be assessed at least 6 months post-surgery, with both case (RTS) and control (non-RTS) groups based on their ability to return to sport.

Ages

18 to 35 years

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male recreational athletes aged 18-35 years. * Participation in sports that involve deceleration, jumping, cutting, or turning (e.g., basketball, soccer, volleyball). * Primary unilateral ACL injury treated with ACL reconstruction using a Peroneus Longus autograft. * Single evaluation 6-12 months after ACL reconstruction. * Completed a standardized postoperative rehabilitation program for ≥6 months, with near-complete rehabilitation and some level of sport participation. * Sufficient knee confidence, no effusion/edema, full knee range of motion, and able to perform all functional tests safely. * Able to provide written informed consent. Exclusion Criteria: * Revision ACL reconstruction. * Prior ACL reconstruction on the ipsilateral or contralateral knee. * Multi-ligament knee injury. * Concomitant meniscal repair or bilateral ACL reconstruction. * Knee pain \> 3/10 at evaluation that prevents or impairs testing. * Incomplete knee extension or knee flexion \< 110°. * Lower-limb fracture or surgery within the past 6 months.

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Conditions

The condition(s) this trial relates to.

Anterior Cruciate Ligament Injuries Athletic Injuries injury Knee Injuries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anterior cruciate ligament (ACL) injury Athletic injuries Knee injuries

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • AHUC

    RECRUITING

    Cairo, Cairo Governorate, 11865, Egypt

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