Targeted radiation shows promise for deadly brain tumors

This pilot study tested a new approach for patients with recurrent high-grade glioma (grade 3 or 4 brain tumors) who have few options left. Researchers used a radioactive drug called 177Lu-PSMA to deliver radiation directly to tumor cells, after first checking if the tumors take up the tracer. Ten participants received up to 6 cycles of therapy, with monitoring for side effects, tumor response, and survival. The goal is to see if this treatment is safe and can improve outcomes for this aggressive cancer.