Smart scans may slash radiation doses for metastatic prostate cancer
NCT ID NCT07674771
First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time
Summary
This early-phase trial explores whether PSMA PET scans can help doctors adjust radiation therapy for men with prostate cancer that has spread to 4 to 20 spots in the body. Participants receive standard hormone therapy plus a special PET scan, then targeted radiation to all visible tumors. A repeat scan after three radiation sessions may allow some tumors to skip the final two sessions if they show a complete response. The goal is to see if this adaptive approach can safely reduce the total radiation dose.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
68Ga-PSMA-11 and adaptive stereotactic ablative radiotherapy (SABR)
What this could lead to
If successful, this approach could reduce the amount of radiation needed for each tumor site, potentially lowering side effects while maintaining cancer control.
What could go wrong
This is a very early-phase trial with only 30 participants, so results may not apply broadly. The imaging and radiation technique may not shrink tumors as expected.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Texas Southwestern Medical Center
Dallas, Texas, 75390, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••