Magic mushroom therapy tested for cancer caregiver stress

NCT ID NCT07048743

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase II trial tests whether a single high dose of psilocybin, given alongside specialized therapy, can help reduce distress in caregivers of people with advanced cancer. Fifteen caregivers in Ontario will receive the drug and be monitored for safety, feasibility, and changes in anxiety. The goal is to see if this approach is practical and acceptable before larger studies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

psilocybin

What this could lead to

If successful, this could point toward a new way to reduce anxiety and distress in caregivers of advanced cancer patients.

What could go wrong

This is a very small, early-phase trial with only 15 participants and no placebo group, so results may not apply broadly. Psilocybin can cause temporary psychological distress or other side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Toronto General Hospital

    RECRUITING

    Toronto, Ontario, M5G 2C4, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••