New program aims to ease emotional toll on brain injury caregivers

NCT ID NCT07331324

Not yet recruiting Symptom relief Sponsor: Massachusetts General Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a program called COMA-F, designed to help caregivers of patients with severe acute brain injury manage emotional distress. The program teaches skills to cope with uncertainty and long-term caregiving challenges. Researchers will compare it to a basic education program in 150 caregivers to see if it reduces anxiety, depression, and stress.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: resilience program (behavioral skills training)
What this could lead to: If it works, this could provide an effective way to reduce anxiety, depression, and stress for caregivers of loved ones with severe brain injury.
What could go wrong: This is a relatively small, early-stage trial (150 people) testing a behavioral program, so results may not apply to all caregivers. The program requires time and effort, and may not help everyone.

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Conditions

The condition(s) this trial relates to.

brain injury Caregiver Burden Coma ocular motor apraxia, Cogan type

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRAIN INJURY CAREGIVER DISTRESS CAREGIVERS COMA EMOTIONAL DISTRESS RESILIENCE

Contacts and locations

Locations

Massachusetts General Hospital

Boston, Massachusetts, 02114, United States
University of Maryland School of Medicine

Baltimore, Maryland, 21201, United States
University of North Carolina School of Medicine

Chapel Hill, North Carolina, 27599, United States

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