COMA

This study tests whether advanced MRI scans that map the brain's structural and functional connections can better predict neurological recovery in coma patients after cardiac arrest than standard methods. Researchers will scan 263 adults who remain unconscious at least 72 hours a…

This observational study tests whether a non-invasive headband called fNIRS can measure brain activity in healthy adults and in people with disorders of consciousness, such as coma, after severe brain injury. Participants wear the headband while receiving gentle touch, listening …

This study follows 2000 adults who are in a coma or have disorders of consciousness after serious brain injuries like stroke, cardiac arrest, or trauma. Researchers collect medical records and later interview survivors or their caregivers about physical and emotional recovery. No…

This study looks at how artificial intelligence (AI) can help emergency call operators quickly identify life-threatening situations like cardiac arrest, stroke, or severe breathing problems. Researchers will analyze millions of past emergency calls to train AI models to recognize…

This study uses a special PET scan to look at dopamine pathways in the brains of people who are in a coma after a severe head injury. Researchers will compare three groups: coma patients, patients who have recovered from coma, and healthy volunteers. The goal is to understand how…

This study tracks 90 coma patients in intensive care to see if their body's natural daily rhythms (like sleep-wake cycles) return as they wake up. Researchers will measure behavior, eye movements, temperature, and urine biomarkers every few hours. The goal is to better understand…

This study tests a new tool called PRECOM that uses brain wave signals to predict whether coma patients after cardiac arrest will wake up within three months. Researchers will enroll 100 adults in French ICUs and compare the tool's predictions to actual outcomes. The goal is to i…