Brain scans reveal dopamine disruption in coma patients
NCT ID NCT06930261
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study uses a special PET scan to look at dopamine pathways in the brains of people who are in a coma after a severe head injury. Researchers will compare three groups: coma patients, patients who have recovered from coma, and healthy volunteers. The goal is to understand how dopamine disruptions relate to consciousness and recovery, which could one day lead to better treatments.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
LBT-999 (a radioactive tracer for PET imaging)
What this could lead to
If successful, this study could reveal how dopamine disruptions affect consciousness after traumatic coma, potentially guiding future treatments to aid recovery.
What could go wrong
This is a small, early-phase imaging study (55 participants) that does not test a treatment. It may not lead to direct patient benefits, and results may not apply to all coma patients.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for SEVERE TRAUMATIC BRAIN INJURY are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
CHU de Toulouse
RECRUITINGToulouse, France
Contact Email: •••••@•••••