Could body clocks predict coma recovery?

NCT ID NCT06245434

First seen Jun 26, 2026 · Last updated Jul 31, 2026 · Updated 3 times

Summary

This study tracks 90 coma patients in intensive care to see if their body's natural daily rhythms (like sleep-wake cycles) return as they wake up. Researchers will measure behavior, eye movements, temperature, and urine biomarkers every few hours. The goal is to better understand how consciousness returns, which could lead to better ways to predict recovery and select patients for future treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could help doctors better predict when a patient might wake from a coma and identify biological markers for future coma treatments.
What could go wrong
This is an early observational study with only 90 participants. It is not testing a treatment, so it may not directly lead to new therapies. Results may not apply to all coma patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Service de Réanimation Polyvalente Neurologique Hôpital Neurologique Pierre Wertheimer

    RECRUITING

    Bron, Lyon, 69500, France

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