Could a Platelet-Rich plasma cocktail beat standard knee arthritis shots?
NCT ID NCT05039463
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial compares two injection treatments for knee osteoarthritis: a combination of platelet-rich plasma (PRP) and hyaluronic acid versus hyaluronic acid alone. Researchers want to see if the combined approach provides better pain relief and function after one year. The study involves 100 adults receiving these injections at a single hospital in France.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
platelet-rich plasma and hyaluronic acid injections
What this could lead to
If effective, this combination could offer a new, non-surgical option to reduce pain and improve function in people with knee osteoarthritis.
What could go wrong
This is a single-center study with 100 participants, and the benefits of PRP injections remain unproven. Results may not apply to all patients.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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CHU Amiens
RECRUITINGAmiens, 80480, France
Contact Phone: •••-•••-•••• Email: •••••@•••••