Could a Platelet-Rich plasma cocktail beat standard knee arthritis shots?
NCT ID NCT05039463
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial compares two injection treatments for knee osteoarthritis: a combination of platelet-rich plasma (PRP) and hyaluronic acid versus hyaluronic acid alone. Researchers want to see if the combined approach provides better pain relief and function after one year. The study involves 100 adults receiving these injections at a single hospital in France.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- platelet-rich plasma and hyaluronic acid injections
- What this could lead to
- If effective, this combination could offer a new, non-surgical option to reduce pain and improve function in people with knee osteoarthritis.
- What could go wrong
- This is a single-center study with 100 participants, and the benefits of PRP injections remain unproven. Results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for HYALURONIC ACID are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CHU Amiens
RECRUITINGAmiens, 80480, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a Low-Carb diet ease knee pain? a study investigates racial differences
- Blocking knee blood vessels may offer new pain relief for severe osteoarthritis
- Which knee implant lasts longer? a Head-to-Head test
- Can cutting carbs curb knee pain? a diet trial puts it to the test
- Can virtual reality make knee pain therapy more engaging?
- Can a stem cell shot rebuild Worn-Out knees?