Can your own blood straighten the curve? PRP takes on Peyronie's
NCT ID NCT04512287
First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time
Summary
This trial tests whether injecting platelet-rich plasma (PRP) — a concentrate made from a person's own blood — into the penile plaque can reduce curvature and ease symptoms in men with Peyronie's disease. Half the participants receive PRP injections and half receive a placebo (saline), with the option to cross over. The study measures changes in penile curvature and symptom scores to see if PRP offers a safe, non-surgical treatment option.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Autologous platelet-rich plasma (PRP) injected into the penile plaque
- What this could lead to
- If effective, PRP injections could offer a non-surgical option to reduce penile curvature and improve symptoms in men with Peyronie's disease.
- What could go wrong
- This is a small phase 2 trial, so results may not be conclusive. PRP is experimental for this condition, and its benefits are uncertain. Risks include injection-related discomfort or infection.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Miami
Miami, Florida, 33136, United States
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