PRP treatment may boost IVF success by reshaping uterine immune cells

NCT ID NCT07535190

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether giving platelet-rich plasma (PRP) inside the uterus can improve the immune environment and thickness of the lining in women undergoing IVF. Researchers will take biopsies before and after PRP to measure changes in immune cells. The goal is to see if PRP can make the uterus more receptive to embryo transfer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

platelet-rich plasma (PRP)

What this could lead to

If it works, this could point toward a simple way to improve IVF success by making the uterine lining more receptive to embryo implantation.

What could go wrong

This is a small, early-phase study with only 50 participants. It focuses on immune cell changes and lining thickness, not directly on pregnancy rates, so benefits remain uncertain.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

female infertility

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Nadezhda Women's Health Hospital

    RECRUITING

    Sofia, Sofia, 1330, Bulgaria

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••