Can a growth factor infusion help women with thin uterine lining get pregnant?

NCT ID NCT07692672

Not yet recruiting Disease control Sponsor: Nanjing University Source: ClinicalTrials.gov ↗

First seen Jul 09, 2026 · Last updated Jul 10, 2026 · Updated 1 time

Summary

This trial tests whether a single infusion of granulocyte colony-stimulating factor (G-CSF) into the uterus can improve pregnancy outcomes in women with thin endometrium (uterine lining) undergoing frozen embryo transfer. Thin endometrium can reduce the chance of pregnancy. The study randomly assigns 620 women to receive either G-CSF or a saline placebo after mild uterine stimulation. The main goal is to see if G-CSF increases the live birth rate.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Granulocyte Colony-Stimulating Factor (G-CSF)
What this could lead to: If it works, this could offer a simple, low-cost way to improve live birth rates for women with thin endometrium undergoing IVF.
What could go wrong: This is a single-center trial, and results may not apply to all patients. G-CSF may not improve outcomes and could carry unknown risks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

female infertility

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FEMALE INFERTILITY THIN ENDOMETRIUM

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

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