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New 'Spot Delete' proton therapy aims to spare prostate cancer patients from bowel troubles

NCT ID NCT06200259

Recruiting now Symptom relief Sponsor: Covenant Health Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a technique called 'Spot Delete' during pencil beam scanning proton therapy for low- and intermediate-risk prostate cancer. The goal is to reduce side effects like diarrhea, rectal bleeding, and urinary problems by preventing proton beams from stopping in sensitive areas. Researchers will compare this method to standard proton planning in 500 participants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Pencil beam scanning proton therapy with Spot Delete technique
What this could lead to
If successful, this technique could reduce painful bowel and bladder side effects from proton therapy for prostate cancer patients.
What could go wrong
This is an early-stage technique with no phase designation, and it may not significantly reduce side effects compared to standard planning. Results are based on reported symptoms, not hard outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

prostate adenocarcinoma prostate cancer prostate carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PROSTATE ADENOCARCINOMA PROSTATE CANCER PROSTATE CARCINOMA

Contacts and locations

Locations

  • Thompson Proton Center

    RECRUITING

    Knoxville, Tennessee, 37909, United States

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