Proton beam therapy takes aim at rare skull base cancer

NCT ID NCT00496522

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 trial is testing whether proton beam therapy, a precise form of radiation, can control skull base chondrosarcoma after surgery. Fifteen participants who have had maximal surgical removal of their tumor will receive daily proton treatments for about 7 weeks. The study will track how long it takes for the cancer to come back and monitor side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Proton beam therapy (a type of radiation that uses protons instead of X-rays to target tumors precisely)

What this could lead to

If successful, this could show that proton beam therapy is an effective way to control skull base chondrosarcoma and delay or prevent its return after surgery.

What could go wrong

This is a small, early-phase trial with only 15 participants, so results may not apply to everyone. The treatment may not prevent recurrence and carries risks from radiation exposure to nearby brain structures.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chondrosarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States