Precision radiation boost aims to tame High-Risk prostate cancer
NCT ID NCT05628363
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a precise radiation technique called adaptive SBRT for men with high-risk or unfavorable intermediate-risk prostate cancer. The treatment targets the prostate and pelvic lymph nodes while giving an extra radiation boost to tumor spots seen on MRI. The goal is to see if this approach is safe and feasible, with fewer than 15% of the 28 participants experiencing severe urinary or bowel side effects within 90 days.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
radiation therapy (SBRT) and androgen deprivation therapy (ADT)
What this could lead to
If successful, this approach could offer a more precise, shorter radiation course for high-risk prostate cancer, potentially reducing side effects while effectively targeting tumors.
What could go wrong
This is a small, early-phase trial (28 participants) focused on safety, not yet proving effectiveness. Side effects from radiation and ADT, such as urinary or bowel issues, are possible.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Washington University School of Medicine
St Louis, Missouri, 63110, United States