Second chance: focused radiation for recurrent prostate cancer

NCT ID NCT03073278

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase trial is testing whether a second, highly targeted dose of radiation (SBRT) can safely treat prostate cancer that has returned after initial radiation therapy. The study involves 36 men whose cancer is confined to a small area of the prostate. The main goal is to check for serious side effects and see if higher radiation doses are feasible.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Stereotactic body radiotherapy (SBRT)

What this could lead to

If successful, this could offer a new treatment option for men whose prostate cancer returns after initial radiation, potentially controlling the disease without more invasive procedures.

What could go wrong

This is a very early, small feasibility trial (36 participants) focused on safety, not effectiveness. The risk of side effects from re-irradiation is unknown, and the approach may not work for all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

prostate cancer prostate carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Royal North Shore Hospital

    RECRUITING

    St Leonards, New South Wales, 2065, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••