Royal North Shore Hospital

This early-phase trial is testing whether a second, highly targeted dose of radiation (SBRT) can safely treat prostate cancer that has returned after initial radiation therapy. The study involves 36 men whose cancer is confined to a small area of the prostate. The main goal is to…

This study tests a newer type of radiation therapy that adjusts to daily changes in a patient's body shape. The goal is to safely use smaller treatment areas to reduce side effects like bladder and bowel problems. About 280 adults with pelvic cancers (prostate, bladder, rectal, a…

This study compares a single, higher-dose palliative radiotherapy session to the usual 5-10 sessions for people with metastatic cancer. The goal is to see if one strong dose can keep symptoms away longer, up to 12 months. About 100 participants will be enrolled to measure how lon…

This study tests a new type of radiation therapy for prostate cancer that adjusts the treatment each day based on changes in the patient's anatomy. The goal is to see if this adaptive approach can safely reduce side effects like bladder and bowel problems. The trial involves 130 …

This study tests whether 3D-printed custom applicators can deliver radiation more precisely than standard cylinder applicators for gynecologic cancers like endometrial, vaginal, and vulvar cancer. Ten participants will receive brachytherapy with a personalized 3D-printed mold. Th…

This study compares two ways of outlining tumors for breast cancer radiation: one done entirely by hand by a doctor, and one where artificial intelligence (AI) helps create the outline. The goal is to see if AI-assisted contouring is just as good and whether it saves time. About …