Daily tailored radiation may spare prostate cancer patients from harsh side effects

NCT ID NCT06547398

Recruiting now Symptom relief Sponsor: Royal North Shore Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new type of radiation therapy for prostate cancer that adjusts the treatment each day based on changes in the patient's anatomy. The goal is to see if this adaptive approach can safely reduce side effects like bladder and bowel problems. The trial involves 130 men and has two phases: first checking if the new workflow is practical, then testing if smaller radiation margins can lower toxicity.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Adaptive radiotherapy (radiation therapy that adjusts daily to changes in anatomy)
What this could lead to: If successful, this approach could reduce side effects like urinary and bowel problems for men receiving radiation for prostate cancer.
What could go wrong: This is an early feasibility study with only 130 participants, so results may not apply widely. The technology is new and may not be practical in all clinics.

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Conditions

The condition(s) this trial relates to.

prostate cancer prostate neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PROSTATIC NEOPLASMS

Contacts and locations

Locations

Northern Sydney Cancer Centre, Royal North Shore Hospital
RECRUITING

St Leonards, New South Wales, 2065, Australia

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