MRI-Guided radiation: a sharper weapon against prostate cancer?

NCT ID NCT00913939

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new way to deliver high-dose radiation to prostate tumors using real-time MRI guidance. It includes two groups: men whose prostate cancer has returned after prior radiation, and men with advanced cancer receiving standard external beam radiation plus this boost. The goal is to see if MRI guidance improves accuracy and tumor targeting in up to 500 patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

MRI-guided HDR brachytherapy

What this could lead to

If successful, this approach could make prostate cancer treatment more precise, potentially reducing side effects and improving outcomes for patients with recurrent or advanced disease.

What could go wrong

This is a pilot study focused on technical performance, not yet proven to improve survival. The procedure is complex and may carry risks like bleeding, infection, or urinary problems.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

prostate cancer prostate carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University Health Network, Princess Margaret Hospital

    RECRUITING

    Toronto, Ontario, M5G 2M9, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••