Shorter radiation may spare side effects for prostate cancer patients

NCT ID NCT05038332

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a shorter, more intense radiation course (SBRT, about 2 weeks) is gentler on quality of life than the standard 4-week course for men with prostate cancer who have had their prostate removed. About 136 men will be randomly assigned to one of the two schedules. The main goal is to compare bowel and urinary side effects two years after treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
radiation therapy
What this could lead to
If it works, this could show that a shorter, more intense radiation course (SBRT) causes fewer side effects and better quality of life than the standard longer course for prostate cancer patients after surgery.
What could go wrong
This is a small, early-phase trial (136 people) comparing two radiation schedules. It focuses on quality of life, not cancer control, so it may not change standard care. Side effects from SBRT could be worse for some patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Michigan Rogel Cancer Center

    RECRUITING

    Ann Arbor, Michigan, 98107, United States

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