Scientists hunt for the most stubborn prostate cancer cells inside human tumors
NCT ID NCT02095249
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at prostate cancer tissue from men undergoing prostate removal surgery to find cells that may be especially aggressive and resistant to treatment. Researchers give a special dye (pimonidazole) before surgery to mark oxygen-starved areas, then analyze the removed prostate for stem-like cells and low-oxygen zones. The goal is to understand which cells drive cancer recurrence and spread, so future treatments can target them more effectively.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Pimonidazole
What this could lead to
If successful, this could help identify which prostate cancer cells are most resistant to treatment, pointing toward more targeted therapies.
What could go wrong
This is a small, early-stage observational study in 39 men. It aims to understand biology, not test a treatment, so direct patient benefits are uncertain.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University Health Network
Toronto, Ontario, M5G2M9, Canada