2,000 men with prostate cancer join gene study to unlock disease secrets

NCT ID NCT04706663

Recruiting now Knowledge-focused Sponsor: National Cancer Institute (NCI) Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 7 times

Summary

This study follows 2,000 men with prostate cancer who have certain gene mutations. Researchers will track their health over many years to see how these genes relate to cancer growth, treatment response, and survival. Participants do not need to visit the hospital regularly; most follow-up is by phone or email.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help doctors better predict how prostate cancer will behave and which treatments might work best based on a person's genes.
What could go wrong: This is an observational study, not a treatment trial. It will not directly test any new drug or therapy, so it may not lead to immediate changes in care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

inherited disease susceptibility prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PROSTATE CANCER

Contacts and locations

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Locations

Dana Farber Cancer Institute, Boston, MA
RECRUITING

Boston, Massachusetts, 02215, United States
Memorial Sloan Kettering Cancer Center
RECRUITING

New York, New York, 10007, United States
Mount Sinai Hospital
NOT_YET_RECRUITING

New York, New York, 10029, United States
National Institutes of Health Clinical Center
RECRUITING

Bethesda, Maryland, 20892, United States
NorthShore University HealthSystem
RECRUITING

Evanston, Illinois, 60201, United States
Oregon Health Sciences University
NOT_YET_RECRUITING

Portland, Oregon, 97239, United States
University of California San Diego
RECRUITING

La Jolla, California, 92093, United States
University of California San Francisco
RECRUITING

San Francisco, California, 94143, United States

Contact Email: •••••@•••••
University of Michigan
NOT_YET_RECRUITING

Ann Arbor, Michigan, 48109, United States
University of Washington
RECRUITING

Seattle, Washington, 98195, United States
Weill Cornell Medicine
NOT_YET_RECRUITING

New York, New York, 10065, United States

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