New study tests if GPS and MRI can keep men off the operating table
NCT ID NCT05424783
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether giving men with low-risk prostate cancer two extra tests—a genomic test (GPS) and a special MRI—helps them stick with active surveillance (monitoring instead of immediate treatment). Researchers will track 222 men for 18 months to see if these tests improve safety and reduce unnecessary biopsies. The goal is to find the right balance between catching dangerous cancers and avoiding overtreatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Genomic Prostate Score assay and multi-parametric MRI
What this could lead to
If successful, this could show that adding these tests helps men safely avoid or delay aggressive treatment, improving quality of life.
What could go wrong
This is an observational study, not a treatment trial. The tests may cause false alarms leading to unnecessary procedures, and results may not apply to all groups.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Northwestern University
ACTIVE_NOT_RECRUITINGChicago, Illinois, 60611, United States
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University of Illinois at Chicago
RECRUITINGChicago, Illinois, 60612, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••