No antibiotics before prostate biopsy? new study checks safety

NCT ID NCT06359964

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looked at whether it is safe to skip antibiotics before a prostate biopsy. Researchers followed 1753 men who had a biopsy through the perineum (the area between the scrotum and anus). They compared infection rates in those who did not get antibiotics to existing data from patients who did. The goal was to see if avoiding antibiotics increases the risk of serious infections like sepsis or hospitalization.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

What this could lead to
If successful, this could show that skipping antibiotics before prostate biopsy is safe, reducing antibiotic use and resistance.
What could go wrong
This is an observational study, not a randomized trial, so results may be less reliable. Infection risks without antibiotics could still be higher for some patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Prince of Wales Hospital

    Shatin, Hong Kong

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Other studies related to the condition(s) this trial covers.