Can a longer overnight fast help men on prostate cancer treatment?

NCT ID NCT07462403

Completed Symptom relief Sponsor: Thomas Jefferson University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This small pilot study tested a 3-month program where men with prostate cancer on hormone therapy were encouraged to fast for 12 to 16 hours each night, supported by weekly coaching calls and text messages. The 40 participants found the program feasible and satisfying, with some showing weight loss and improved quality of life. However, the results were not strong enough to prove the program works, so larger studies are needed.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: prolonged nightly fasting plus telehealth coaching
What this could lead to: If it works, this could offer a simple lifestyle approach to help men on hormone therapy manage weight and improve quality of life.
What could go wrong: This was a small pilot study with only 40 participants, and the improvements seen were not statistically significant. Larger trials are needed to confirm any real benefit.

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Conditions

The condition(s) this trial relates to.

prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PROSTATE CANCER

Contacts and locations

Locations

Thomas Jefferson University Hospital

Philadelphia, Pennsylvania, 19107, United States

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