Could probiotics tame Chemo's worst symptoms?

NCT ID NCT06772090

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether taking probiotic supplements can help reduce common chemotherapy side effects like nausea, diarrhea, and loss of appetite in people with stage III colon cancer. Forty adults will be randomly assigned to receive either probiotics or a placebo during their chemo treatment. The main goal is to see if a larger, more definitive trial is even possible, so results will focus on how many people complete the study and how many side effects occur.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Probiotic supplement (Lactobacillus and Bifidobacterium)

What this could lead to

If it works, this could point toward a simple way to reduce common chemo side effects like nausea and diarrhea for people with colon cancer.

What could go wrong

This is a very small, early feasibility trial with only 40 people. It is designed to test whether a larger study is possible, not to prove the probiotics work. Results may not apply to other cancers or treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for SOLID TUMOR, ADULT are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

colon carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••