New anesthesia bundle cuts deadly lung complications in half?

NCT ID NCT04108130

First seen Oct 31, 2025 · Last updated May 12, 2026 · Updated 30 times

Summary

This study tested whether a set of anesthesia techniques could lower the risk of serious lung complications after open abdominal surgery. About 794 adults at intermediate or high risk for lung problems were randomly assigned to receive either the special anesthesia bundle or usual care. The goal was to see if the bundle reduced the number and severity of lung issues in the first week after surgery.

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Contacts and locations

Locations

  • Beth Israel Deaconess Hospital

    Boston, Massachusetts, 02215, United States

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Columbia University Medical Center

    New York, New York, 10032, United States

  • Duke University

    Durham, North Carolina, 27710, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Memorial Sloan Kettering

    New York, New York, 10065, United States

  • Montefiore Hospital

    The Bronx, New York, 10467, United States

  • Northwestern University

    Evanston, Illinois, 60208, United States

  • South Florida Veterans Affairs Foundation for Research and Education, Inc.

    Miami, Florida, 33125, United States

  • Stanford University

    Stanford, California, 94305, United States

  • Univerisity of Massachusetts Amherst Center

    Worcester, Massachusetts, 01655, United States

  • University of California - San Francisco

    San Francisco, California, 94115, United States

  • University of Colorado, Anschutz Medical Campus

    Aurora, Colorado, 80045, United States

  • University of Nebraska Medical Center

    Omaha, Nebraska, 68198, United States

  • University of Rochester

    Rochester, New York, 14642, United States

Conditions

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