5-Day radiation before sarcoma surgery could spare healthy tissue

NCT ID NCT06905132

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a 5-day course of radiation given before surgery for soft tissue sarcoma in the arms, legs, or trunk. The goal is to see if this shorter treatment is safe and effective at controlling the cancer while preserving more healthy tissue. About 40 adults will receive radiation daily for a week, followed by standard surgery 2-6 weeks later. Researchers will monitor wound healing and tumor response.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Hypofractionated radiation therapy (a shorter, higher-dose radiation course over 5 days)

What this could lead to

If successful, this could offer a more convenient and less disruptive treatment option for soft tissue sarcoma patients, potentially reducing side effects and preserving healthy tissue.

What could go wrong

This is a small, early-phase trial with only 40 participants, so results may not apply to all patients. The shorter radiation course may not be as effective as standard treatment and could still cause wound complications or other side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

sarcoma soft tissue sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Medical University of South Carolina

    RECRUITING

    Charleston, South Carolina, 29401, United States

    Contact