Could pain relief make a lifesaving breathing procedure safer for preterm infants?
NCT ID NCT05065424
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether giving two medicines (atropine and fentanyl) before a less invasive breathing treatment helps preterm babies have fewer dangerous drops in heart rate and oxygen levels. Fifty-eight babies born at 29 weeks or later took part. The goal is to see if premedication makes the procedure safer and more comfortable.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- atropine and fentanyl
- What this could lead to
- If it works, this could make a common breathing procedure safer and less stressful for preterm babies.
- What could go wrong
- This is a small, single-center trial with only 58 babies, so results may not apply widely. The drugs themselves can cause side effects like slowed breathing.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Parkland Health and Hospital System
Dallas, Texas, 75390, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can an Oxygen-Boosting drug help when all else fails?
- Can a steroid shot into the windpipe protect preemies' lungs?
- Gentler breathing support may help preterm babies avoid breathing tubes
- Ultrasound may help doctors time lifesaving lung treatment for preterm infants