New pill combo may ease root canal pain without harsh drugs
NCT ID NCT06298383
First seen Nov 19, 2025 · Last updated May 17, 2026 · Updated 24 times
Summary
This study tested whether taking a combination of trypsin, bromelain, and rutoside before a root canal can improve the success of local anesthesia and reduce pain after the procedure. 124 adults with painful tooth inflammation (symptomatic irreversible pulpitis) participated. The goal was to find a safer anti-inflammatory option than standard NSAIDs or steroids.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Faculty of Dentistry, Cairo University
Cairo, 4450113, Egypt
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Faculty of Oral and Dental Medicine, Egyptian Russian University
Cairo, Cairo Governorate, 11829, Egypt
Conditions
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