New pill combo may ease root canal pain without harsh drugs
NCT ID NCT06298383
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether taking a combination of trypsin, bromelain, and rutoside before a root canal helps the numbing shot work better and lowers pain after the procedure. 124 adults with painful tooth inflammation (pulpitis) took the medication or a placebo. The goal was to improve anesthesia success and reduce post-treatment pain using a gentler anti-inflammatory option.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Faculty of Dentistry, Cairo University
Cairo, 4450113, Egypt
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Faculty of Oral and Dental Medicine, Egyptian Russian University
Cairo, Cairo Governorate, 11829, Egypt