New MRI technique may tell doctors if cancer is gone before surgery

NCT ID NCT06719414

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a special type of MRI, called amide proton transfer-weighted imaging, can accurately predict if rectal cancer has completely disappeared after chemotherapy and radiation. Researchers will compare the MRI results with the actual tissue removed during surgery. The goal is to help doctors know if surgery is still needed, potentially avoiding unnecessary operations. About 320 adults with locally advanced rectal cancer who have completed neoadjuvant therapy will participate.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

rectal cancer rectal neoplasm rectum adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Sixth Affiliated Hospital, Sun Yat-sen University

    RECRUITING

    Guangzhou, Guangdong, 510655, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xinyi People's Hospital

    NOT_YET_RECRUITING

    Maoming, Guangdong, China

    Contact Phone: •••-•••-••••